is simparica safe for mdr1 dogs
To help with this, the product can be applied in more than one line between the neck and shoulder blades. Many veterinary clinics keep some in stock for their clients, and it is also available at online stores like 1-800-PET-MEDS or Chewy. Bottom line is that Simparica will probably be fine for your dog, but there is a slight risk that it wont. The agency is asking the manufacturers to make the changes to the product labeling in order to provide veterinarians and pet owners with the . My other vet never brought this up when discussing my MAS. Thank you for the useful information which is a little easier (clearer) to understand than most. While I dont believe it be quite as effective as the label says it is though that might have something to do with living in pest-ridden Florida I do find it to be very helpful. Another thing to research and to ask your personal vet about might be potential drug/drug interactions between the Trazadone and Effifax, or whichever parasite preventives you choose to use in the future. Dr. Morgan concluded her story with: Be your pets advocate. Wow! This gene specifically codes for P-glycoprotein, which is responsible for transporting certain drugs out of the brain. Ive talked to Collie and Aussie owners who absolutely swear by their Seresto collars and others who are livid because they made their dogs neck bald! Revolution, along with a product called Stronghold, tested safest in clinical trials of heartworm medications. On the second dose she went into an extreme false heat. This was shown by panting , pacing, and curling her tail to show being receptive for breeding. Besides safety, Revolution is an attractive option because of its ease of application (topical squeeze-on tube) and versatility in treating heartworm, fleas, dog ticks, sarcoptic mange, and even ear mites. GSD is an abbreviation for German Shepherd Dog , Thankyou so much for your articleso much great infoI have a 7 month mini Aussieon Symparticabut not feeling good about itshe hasnt been tested for MRD1 but I know I have to change it upthankyou again , Youre very welcome, and good luck with your pup! So far, noone has the answer to this seemingly-simple question as to what ticks their product actually acts against. Would this be your recommendation? (Some of the links lead to peer-reviewed scientific articles, so have fun with those if you want the bare, dusty facts.). I just took her off Sentinel Flavor Tabs. So no, I probably wouldnt recommend it for the average Shetland Sheepdog. It will make your dog smell absolutely yummy while protecting them from fleas, ticks, black flies, and mosquitoes. (More on those later.). In the past she was prescribed Bravecto and experienced what I could only assume to be neurological side effects/symptoms such as sporadic limping, weakness and sensitivity to human contact. (I didnt find the information about the 6 reported seizures until after I had already given it to my dogs and seen no ill effects from it.) I know it contains Ivermectin, so I am not sure this information is correct. Thank you for bringing this to my attention! Safe in breeding, pregnant and lactating dogs. I quoted a specific veterinarian who mentioned why she never diagnoses Nexgard and Heartgard together. Combining spinosad (the flea control ingredient in Comfortis and Trifexis) with the high doses of ivermectin and milbemycin oxime used to treat demodectic and sarcoptic mange increases the potential for neurological side effects. I looked up potential side effects for the new pill, and sure enough, the product info for the pain medication specifically advised that it should not be taken with blood pressure medication. But I do think K9 Advantix is a good choice for Collies who arent overly sensitive. I went back and edited my comment for consistency. Turns out it is also used for the treatment and prevention of roundworms and lungworm nemotodes in dogs, according to Vet Shop Max. However, in such sensitive breeds (which may include, but not necessarily limited to, Collies and related breeds), the recommended dose should be strictly observed. MDR1 is a drug sensitivity that affects the majority - approximately 70%-75% of Rough and Smooth Collies in the USA and potentially worldwide. And safe travels to you and Lola in the future. On the downside, its efficacy only lasts for about a day. For me, every medicine has its side effects, and it really comes down to weighing the risk of side effects against the risks posed by parasites. Is Simparica Safe for Dogs? Another safe heartworm medication is the daily dimmitrol. There werent as many seizures reported as with Nexgard, but it did have several more reported than Bravecto. Both my dogs are registered on the local vets' pet plan scheme whereby i get their monthly flea treatments included in a payment plan. My two cats were father and son so probably carried the same gene. In regard to natural products, Ive used some organic topicals, which Ill list later, that aresomewhat effective as repellents; but unfortunately I do not know of any natural pest control products that actually work as well as chemical-based ones. My dog has been tested and is mutant/normal (MDR1). I love that it quickly kills adult fleas andfour kinds of ticks: American dog tick, brown dog tick, lone star tick, and black-legged tick. Id like to have a Border Collie one day, but as I have some health issues Im not sure I could keep up with one. I have two Rough Collies who are MDR1 carriers and an Aussie mix, so I have a vested interest in everything Ive researched. As far as which flea and tick protection would be safest for a puppy, some of my top picks are Capstar (for instant relief, not necessarily long-term use), a natural oil spray like Natural Chemistry or Wondericide, or something not very harsh like Frontline Plus. However, a dog with . It is safe for use with anthelmintics like heartworm meds and has no known negative drug-drug interactions. Best of luck to you and Sugar! THREE OF THE 8 FEMALES WENT INTO ESTRUS. Based on my findings, Im not convinced of its superior safety. Took that collar right off her. For the majority of dogs, Advecta is probably fine! My Vet told me Trifexis was safe to give them. We gave her the first dose in late February and there were no adverse side effects for Sugar. Are you referring to Advantage Multi, Advantage II, or a different product I didnt cover in the article? Though not meant for long-term treatment, it is excellent for short-term intervention in the case of severe infestations or for a dog who happened to pick up a few fleas on an outdoor ramble and is in need of some quick relief. When reading about Seresto, their website said it doesnt work well on dogs with heavy coats, ie. Last time I took my Collies to a pet store here in parasite-infested Florida, I asked one of the clerks what they sold the most of as far as flea and tick preventives. From an MDR1 standpoint, Simparica is *technically* safe; but I am leery of it considering the FDA warning about isoxazolines (-laner medications) I discussed in the article. We do eat it! Honestly, Id use it even if it was completely ineffective, because it makes my dogs smell delicious. If youre concerned about a possible hormonal imbalance being triggered by Effifax, it might be worth looking into an alternate flea control product that does not contain Fipronil. However, heartworm preventatives are still safe for MDR1 drug-sensitive dogs to take at low, FDA-approved dosages. Research efforts are underway to determine if new veterinary and human drug products could be problematic for dogs with the MDR1 mutation. Do you know what the ingredients are in the medicated shampoo? Also, Permethrin is one of the active ingredients in K9 Advantix II, an effective spot-on product Ive used on my Aussie mix with no ill effects. I have 7 collies and I am reluctant to put them on anything thats not natural , we did get a kitten and found a flea so looking for something to treat all as a precautionary for a month as we are in winter season in Northern Ontario Canada. I have a female 3 year old collie. Frontline Gold and Frontline Shield. Personalizing your pets health care. We have a almost 10 year old tricolor rough collie, named Hollie. The tail curling and pacing lasted over a week. Be prepared to answer questions about whether your dog had a previous history with seizures, has any drug sensitivities, if anything else could possibly have triggered a seizure, and if she has had any seizures since the collar was removed. All the available heartworm medications on the market are a variation of what is known clinically as a ML (macrocyclic lactone) compound. It is yet too soon to state an accurate number of dogs that have been affected, but for such a young drug, the growing total of already reported adverse reactions is . However, it would be best to have a veterinarian collect a skin scraping to examine under a microscope and determine whether skin irritation is caused by demodectic or sarcoptic mites, as the causes and treatments differ between the two types. It is easily administered since it is a flavored chewable, and it takes care of heartworms and fleas. So called vet and they said topically we should try Parastar Plus. I have been told that Advocate is safe for him at the recommended dose. We took her to a vet who is very experienced with collies (she helps with a rescue) and has assured me that Simpirica Trio is safe. His food hadnt changed, so Im nearly certain it was an adverse reaction to the Credelio. Its a nice alternative to Vectra 3D since its not as potent (so less chance for irritation), yet it also has some repellent properties. Bear in mind that my opinion is by no means professional, but personally Id go with your first vets prescription. These generics include Tri-Heart Plus, Iverhart Plus, and Nuheart. According to the product description, side effects as a result of Trifexis are rare, but can be as severe as seizures or even a coma. Additionally, it can be used to treat and control sarcoptic mange. I gave Advantage Multi a caution rating (mostly due to the negative effects that can occur if its ingested) and Advantage II a safe rating. (My dogs dont groom each other or really play that way now that theyre older and settled, so I feel comfortable using topicals now.) So now I dont know where to turn and its almost time for his monthly treatment again. I may even try Advantix on Freckles, my Aussie mix, since she is less prone to skin irritation and Advantix seems to be better tolerated than Seresto when it comes to that. Does your veterinarian give other reasons for prescribing Credelio vs. similar brands? I appreciate the research in this thank you! Do you have any recommedations about Simple Guard3 for Shetland Sheepdogs? It probably is the safest as it is aimed only at preventing heartworm. Vectra is a rather strong product that I wont personally recommend, as so many dogs in the Collie family have sensitivities. Given your knowledge, would you suggest Credelio vs. K9 Advantix II (if tolerated) ? However, as it is the amped-up version of Frontline Plus and contains 3 active ingredients, its always wise to check the application site for adverse skin reactions. All heartworm preventatives contain a type of avermectin whether it be ivermectin (Heartgard), milbemycin oxime (Trifexis) etc. Vectras brag is that it repels and kills fleas, five kinds of ticks, flies, mosquitoes, and mites; however, its use is not worth its risk. I cant promise that it will be 100% effective, and one or two ticks may still latch on but Ive seen zero ticks on my dogs since I started using the Natural Chemistry spray in conjunction with Frontline Plus. Advocate is safe for him is simparica safe for mdr1 dogs the recommended dose at the recommended dose veterinary. Simple Guard3 for Shetland Sheepdogs anthelmintics like heartworm meds and has no known negative drug-drug interactions safest! 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